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Metformin Inhibits Migration and Invasion by Suppressing ROS Production and COX2 Expression in MDA-MB-231 Breast Cancer Cells

Background: Several mechanisms of action have been proposed to explain the apparent antineoplastic functions of metformin, many of which are observed at high concentrations that may not be reflective of achievable tissue concentrations. We propose that metformin at low concentrations functions to in...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Schexnayder, Chandler, Broussard, Kiera, Onuaguluchi, Demitrius, Poché, Anthony, Ismail, Moamen, McAtee, LeFontae, Llopis, Shawn, Keizerweerd, Amber, McFerrin, Harris, Williams, Christopher
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274682/
https://ncbi.nlm.nih.gov/pubmed/30469399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113692
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