Metformin Inhibits Migration and Invasion by Suppressing ROS Production and COX2 Expression in MDA-MB-231 Breast Cancer Cells

Background: Several mechanisms of action have been proposed to explain the apparent antineoplastic functions of metformin, many of which are observed at high concentrations that may not be reflective of achievable tissue concentrations. We propose that metformin at low concentrations functions to in...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Schexnayder, Chandler, Broussard, Kiera, Onuaguluchi, Demitrius, Poché, Anthony, Ismail, Moamen, McAtee, LeFontae, Llopis, Shawn, Keizerweerd, Amber, McFerrin, Harris, Williams, Christopher
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274682/
https://ncbi.nlm.nih.gov/pubmed/30469399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113692
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