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Deciphering Molecular and Phenotypic Changes Associated with Early Autoimmune Disease in the Aire-Deficient Mouse Model of Sjögren’s Syndrome

Sjögren’s syndrome (SS) is characterized by extensive lymphocytic infiltration of the salivary and lacrimal gland (LG), resulting in acinar cell destruction and organ dysfunction. The underlying pathogenesis of SS remains largely unknown, and studies historically focus on defining late-stage disease...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chen, Feeling YuTing, Gaylord, Eliza, McNamara, Nancy, Knox, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274681/
https://ncbi.nlm.nih.gov/pubmed/30453645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113628
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