Spontaneous Development of Autoimmune Uveitis Is CCR2 Dependent

Development of novel strategies to treat noninfectious posterior uveitis is an ongoing challenge, in part because of limited availability of animal models that mimic the naturally occurring disease in humans. Mice deficient in the autoimmune regulatory gene Aire develop a spontaneous T-cell and macr...

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Detalhes bibliográficos
Main Authors: Chen, YuTing Feeling, Zhou, Delu, Metzger, Todd, Gallup, Marianne, Jeanne, Marion, Gould, Douglas B., Anderson, Mark S., McNamara, Nancy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044718/
https://ncbi.nlm.nih.gov/pubmed/24736166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.02.024
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