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Deciphering Molecular and Phenotypic Changes Associated with Early Autoimmune Disease in the Aire-Deficient Mouse Model of Sjögren’s Syndrome

Sjögren’s syndrome (SS) is characterized by extensive lymphocytic infiltration of the salivary and lacrimal gland (LG), resulting in acinar cell destruction and organ dysfunction. The underlying pathogenesis of SS remains largely unknown, and studies historically focus on defining late-stage disease...

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Pubblicato in:Int J Mol Sci
Autori principali: Chen, Feeling YuTing, Gaylord, Eliza, McNamara, Nancy, Knox, Sarah
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274681/
https://ncbi.nlm.nih.gov/pubmed/30453645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113628
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