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Deciphering Molecular and Phenotypic Changes Associated with Early Autoimmune Disease in the Aire-Deficient Mouse Model of Sjögren’s Syndrome

Sjögren’s syndrome (SS) is characterized by extensive lymphocytic infiltration of the salivary and lacrimal gland (LG), resulting in acinar cell destruction and organ dysfunction. The underlying pathogenesis of SS remains largely unknown, and studies historically focus on defining late-stage disease...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Chen, Feeling YuTing, Gaylord, Eliza, McNamara, Nancy, Knox, Sarah
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274681/
https://ncbi.nlm.nih.gov/pubmed/30453645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113628
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