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Synthesis and Biological Evaluation of Novel (99m)Tc(CO)(3)-Labeled Thymidine Analogs as Potential Probes for Tumor Proliferation Imaging

Achieving a (99m)Tc labeled thymidine radiotracer for single photon emission tomography (SPECT) is considered to be of interest. In this study, four novel thymidine analogs, 6a, 6b, 6c and 6d, were successfully synthesized via “click reaction” route and then radiolabeled using a [(99m)Tc(CO)(3)](+)...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Duan, Xiaojiang, Liu, Teli, Zhang, Yichun, Zhang, Junbo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274394/
https://ncbi.nlm.nih.gov/pubmed/27104501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21040510
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