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Celastrol Induces Cell Apoptosis and Inhibits the Expression of the AML1-ETO/C-KIT Oncoprotein in t(8;21) Leukemia

Resistance to chemotherapy is a major challenge to improving overall survival in Acute Myeloid Leukemia (AML). Therefore, the development of innovative therapies and the identification of more novel agents for AML are urgently needed. Celastrol, a compound extracted from the Chinese herb Tripterygiu...

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Vydáno v:Molecules
Hlavní autoři: Yu, Xianjun, Ruan, Xuzhi, Zhang, Jingxuan, Zhao, Qun
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274014/
https://ncbi.nlm.nih.gov/pubmed/27144550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21050574
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