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Inhibitory Interactions of Aspalathus linearis (Rooibos) Extracts and Compounds, Aspalathin and Z-2-(β-d-Glucopyranosyloxy)-3-phenylpropenoic Acid, on Cytochromes Metabolizing Hypoglycemic and Hypolipidemic Drugs

Rooibos extract, due to its glucose and lipid lowering effects, has potential as a nutraceutical for improvement of metabolic dysfunction. Potential herb-drug interactions as a result of the use of natural products are of increasing concern. Cytochrome P450 enzymes, CYP2C8, CYP2C9, and CYP3A4, are i...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Patel, Oelfah, Muller, Christo, Joubert, Elizabeth, Louw, Johan, Rosenkranz, Bernd, Awortwe, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273468/
https://ncbi.nlm.nih.gov/pubmed/27845750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21111515
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