Evaluation of the Enantiomer Specific Biokinetics and Radiation Doses of [(18)F]Fluspidine—A New Tracer in Clinical Translation for Imaging of σ(1) Receptors

The enantiomers of [(18)F]fluspidine, recently developed for imaging of σ(1) receptors, possess distinct pharmacokinetics facilitating their use in different clinical settings. To support their translational potential, we estimated the human radiation dose of (S)-(−)-[(18)F]fluspidine and (R)-(+)-[(...

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Vydáno v:Molecules
Hlavní autoři: Kranz, Mathias, Sattler, Bernhard, Wüst, Nathanael, Deuther-Conrad, Winnie, Patt, Marianne, Meyer, Philipp M., Fischer, Steffen, Donat, Cornelius K., Wünsch, Bernhard, Hesse, Swen, Steinbach, Jörg, Brust, Peter, Sabri, Osama
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273209/
https://ncbi.nlm.nih.gov/pubmed/27598110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21091164
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