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Structure Based Modeling of Small Molecules Binding to the TLR7 by Atomistic Level Simulations

Toll-Like Receptors (TLR) are a large family of proteins involved in the immune system response. Both the activation and the inhibition of these receptors can have positive effects on several diseases, including viral pathologies and cancer, therefore prompting the development of new compounds. In o...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Gentile, Francesco, Deriu, Marco A., Licandro, Ginevra, Prunotto, Alessio, Danani, Andrea, Tuszynski, Jack A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272798/
https://ncbi.nlm.nih.gov/pubmed/26007168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20058316
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