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Design, Synthesis, and Cytotoxicity of Perbutyrylated Glycosides of 4β-Triazolopodophyllotoxin Derivatives

A series of novel perbutyrylated glycosides of 4β-triazolopodophyllotoxin derivatives were synthesized by utilizing the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction. Evaluation of cytotoxicity against a panel of five human cancer cell lines (HL-60, SMMC-7721, A-549, MCF-7, SW480) usi...

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Publicat a:Molecules
Autors principals: Zi, Cheng-Ting, Liu, Zhen-Hua, Li, Gen-Tao, Li, Yan, Zhou, Jun, Ding, Zhong-Tao, Hu, Jiang-Miao, Jiang, Zi-Hua
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272287/
https://ncbi.nlm.nih.gov/pubmed/25690288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20023255
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