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Synthesis of New Quinoxalines Containing an Oxirane Ring by the TDAE Strategy and in Vitro Evaluation in Neuroblastoma Cell Lines

Neuroblastoma is an aggressive pediatric malignancy with significant chemotherapeutic resistance. In order to obtain new compounds active on neuroblastoma cell lines, we investigated the reactivity of carbanion formed via TDAE in quinoxaline series. The new synthesized compounds were tested for thei...

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Publicado en:Molecules
Autores principales: Montana, Marc, Correard, Florian, Khoumeri, Omar, Esteve, Marie-Anne, Terme, Thierry, Vanelle, Patrice
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271844/
https://ncbi.nlm.nih.gov/pubmed/25237753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules190914987
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