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Synthesis of New Quinoxalines Containing an Oxirane Ring by the TDAE Strategy and in Vitro Evaluation in Neuroblastoma Cell Lines

Neuroblastoma is an aggressive pediatric malignancy with significant chemotherapeutic resistance. In order to obtain new compounds active on neuroblastoma cell lines, we investigated the reactivity of carbanion formed via TDAE in quinoxaline series. The new synthesized compounds were tested for thei...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Montana, Marc, Correard, Florian, Khoumeri, Omar, Esteve, Marie-Anne, Terme, Thierry, Vanelle, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271844/
https://ncbi.nlm.nih.gov/pubmed/25237753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules190914987
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