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Amino Acid Derivatives of Ligustrazine-Oleanolic Acid as New Cytotoxic Agents
A series of novel ligustrazine-oleanolic acid (TOA) derivatives were designed, and synthesized by conjugating amino acids to the 3-hydroxy group of TOA by ester bonds. Their cytotoxicity was evaluated on four cancer cell lines (HepG2, HT-29, Hela and BGC-823) by standard MTT assays. The ClogP values...
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| 出版年: | Molecules |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6271079/ https://ncbi.nlm.nih.gov/pubmed/25387350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191118215 |
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