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Applications of Copper-Catalyzed Click Chemistry in Activity-Based Protein Profiling

Activity-based protein profiling (ABPP) is a chemical proteomic technique that enables the interrogation of protein activity directly within complex proteomes. Given the dominant role of posttranslational modifications in regulating protein function in vivo, ABPP provides a direct readout of activit...

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Bibliographic Details
Published in:Molecules
Main Authors: Martell, Julianne, Weerapana, Eranthie
Format: Artigo
Language:Inglês
Published: MDPI 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270908/
https://ncbi.nlm.nih.gov/pubmed/24473203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19021378
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