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Comparative Analysis of Click Chemistry Mediated Activity-Based Protein Profiling in Cell Lysates

Activity-based protein profiling uses chemical probes that covalently attach to active enzyme targets. Probes with conventional tags have disadvantages, such as limited cell permeability or steric hindrance around the reactive group. A tandem labeling strategy with click chemistry is now widely used...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Yang, Yinliang, Yang, Xiaomeng, Verhelst, Steven H. L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270401/
https://ncbi.nlm.nih.gov/pubmed/24126377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181012599
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