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Comparative Analysis of Click Chemistry Mediated Activity-Based Protein Profiling in Cell Lysates

Activity-based protein profiling uses chemical probes that covalently attach to active enzyme targets. Probes with conventional tags have disadvantages, such as limited cell permeability or steric hindrance around the reactive group. A tandem labeling strategy with click chemistry is now widely used...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Yang, Yinliang, Yang, Xiaomeng, Verhelst, Steven H. L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270401/
https://ncbi.nlm.nih.gov/pubmed/24126377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181012599
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