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Comparative Analysis of Click Chemistry Mediated Activity-Based Protein Profiling in Cell Lysates

Activity-based protein profiling uses chemical probes that covalently attach to active enzyme targets. Probes with conventional tags have disadvantages, such as limited cell permeability or steric hindrance around the reactive group. A tandem labeling strategy with click chemistry is now widely used...

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Publicat a:Molecules
Autors principals: Yang, Yinliang, Yang, Xiaomeng, Verhelst, Steven H. L.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270401/
https://ncbi.nlm.nih.gov/pubmed/24126377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181012599
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