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Synthetic Genistein Glycosides Inhibiting EGFR Phosphorylation Enhance the Effect of Radiation in HCT 116 Colon Cancer Cells

The need to find new EGFR inhibitors for use in combination with radiotherapy in the treatment of solid tumors has drawn our attention to compounds derived from genistein, a natural isoflavonoid. The antiproliferative potential of synthetic genistein derivatives used alone or in combination with ion...

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Bibliographic Details
Published in:Molecules
Main Authors: Gruca, Aleksandra, Krawczyk, Zdzisław, Szeja, Wiesław, Grynkiewicz, Grzegorz, Rusin, Aleksandra
Format: Artigo
Language:Inglês
Published: MDPI 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270897/
https://ncbi.nlm.nih.gov/pubmed/25401399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191118558
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