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Synthetic Genistein Glycosides Inhibiting EGFR Phosphorylation Enhance the Effect of Radiation in HCT 116 Colon Cancer Cells

The need to find new EGFR inhibitors for use in combination with radiotherapy in the treatment of solid tumors has drawn our attention to compounds derived from genistein, a natural isoflavonoid. The antiproliferative potential of synthetic genistein derivatives used alone or in combination with ion...

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Pubblicato in:Molecules
Autori principali: Gruca, Aleksandra, Krawczyk, Zdzisław, Szeja, Wiesław, Grynkiewicz, Grzegorz, Rusin, Aleksandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270897/
https://ncbi.nlm.nih.gov/pubmed/25401399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191118558
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