Sinulariolide Induced Hepatocellular Carcinoma Apoptosis through Activation of Mitochondrial-Related Apoptotic and PERK/eIF2α/ATF4/CHOP Pathway

Sinulariolide, an active compound isolated from the cultured soft coral Sinularia flexibilis, has potent anti-microbial and anti-tumorigenesis effects towards melanoma and bladder cancer cells. In this study, we investigated the effects of sinulariolide on hepatocellular carcinoma (HCC) cell growth...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Chen, Yi-Jen, Su, Jui-Hsin, Tsao, Chia-Yu, Hung, Chun-Tzu, Chao, Hsiang-Hao, Lin, Jen-Jie, Liao, Ming-Hui, Yang, Zih-Yan, Huang, Han Hisang, Tsai, Feng-Jen, Weng, Shun-Hsiang, Wu, Yu-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270604/
https://ncbi.nlm.nih.gov/pubmed/23973991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules180910146
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