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Factors Influencing the Antifolate Activity of Synthetic Tea-Derived Catechins
Novel tea catechin derivatives have been synthesized, and a structure-activity study, related to the capacity of these and other polyphenols to bind dihydrofolate reductase (DHFR), has been performed. The data showed an effective binding between all molecules and the free enzyme, and the dissociatio...
Zapisane w:
| Wydane w: | Molecules |
|---|---|
| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
MDPI
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6270263/ https://ncbi.nlm.nih.gov/pubmed/23863773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18078319 |
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