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Factors Influencing the Antifolate Activity of Synthetic Tea-Derived Catechins

Novel tea catechin derivatives have been synthesized, and a structure-activity study, related to the capacity of these and other polyphenols to bind dihydrofolate reductase (DHFR), has been performed. The data showed an effective binding between all molecules and the free enzyme, and the dissociatio...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijät: Sáez-Ayala, Magalí, Fernández-Pérez, María Piedad, Chazarra, Soledad, Mchedlishvili, Nani, Tárraga-Tomás, Alberto, Rodríguez-López, José Neptuno
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270263/
https://ncbi.nlm.nih.gov/pubmed/23863773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18078319
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