Synthesis of New Acadesine (AICA-riboside) Analogues Having Acyclic d-ribityl or 4-Hydroxybutyl Chains in Place of the Ribose

The antiviral activity of certain acyclic nucleosides drew our attention to the fact that the replacement of the furanose ring by an alkyl group bearing hydroxyl(s) could be a useful structural modification to modulate the biological properties of those nucleosides. Herein, we report on the synthesi...

Full description

Saved in:
Bibliographic Details
Published in:Molecules
Main Authors: D’Errico, Stefano, Oliviero, Giorgia, Borbone, Nicola, Amato, Jussara, Piccialli, Vincenzo, Varra, Michela, Mayol, Luciano, Piccialli, Gennaro
Format: Artigo
Language:Inglês
Published: MDPI 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269997/
https://ncbi.nlm.nih.gov/pubmed/23924994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18089420
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items