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Synthesis of New Acadesine (AICA-riboside) Analogues Having Acyclic d-ribityl or 4-Hydroxybutyl Chains in Place of the Ribose

The antiviral activity of certain acyclic nucleosides drew our attention to the fact that the replacement of the furanose ring by an alkyl group bearing hydroxyl(s) could be a useful structural modification to modulate the biological properties of those nucleosides. Herein, we report on the synthesi...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: D’Errico, Stefano, Oliviero, Giorgia, Borbone, Nicola, Amato, Jussara, Piccialli, Vincenzo, Varra, Michela, Mayol, Luciano, Piccialli, Gennaro
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269997/
https://ncbi.nlm.nih.gov/pubmed/23924994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18089420
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