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Novel Conformationally Constrained Analogues of Agomelatine as New Melatoninergic Ligands
Novel conformationally restricted analogues of agomelatine were synthesized and pharmacologically evaluated at MT(1) and MT(2) melatoninergic receptors. Replacement of the N-acetyl side chain of agomelatine by oxathiadiazole-2-oxide (compound 3), oxadiazole-5(4H)-one (compound 4), tetrazole (compoun...
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| 出版年: | Molecules |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6269769/ https://ncbi.nlm.nih.gov/pubmed/23262445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18010154 |
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