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Novel Conformationally Constrained Analogues of Agomelatine as New Melatoninergic Ligands
Novel conformationally restricted analogues of agomelatine were synthesized and pharmacologically evaluated at MT(1) and MT(2) melatoninergic receptors. Replacement of the N-acetyl side chain of agomelatine by oxathiadiazole-2-oxide (compound 3), oxadiazole-5(4H)-one (compound 4), tetrazole (compoun...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6269769/ https://ncbi.nlm.nih.gov/pubmed/23262445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18010154 |
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