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Evaluation of droplet digital PCR and next generation sequencing for characterizing DNA reference material for KRAS mutation detection

KRAS gene mutations are predictive markers of non-response to anti-epidermal growth factor receptor. An increasing number of techniques are being developed to detect KRAS mutations. To obtain consistent and comparable results, a traceable reference material (RM) is necessary for validation the routi...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Dong, Lianhua, Wang, Shangjun, Fu, Boqiang, Wang, Jing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269532/
https://ncbi.nlm.nih.gov/pubmed/30504843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27368-3
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