Measuring KRAS Mutations in Circulating Tumor DNA by Droplet Digital PCR and Next-Generation Sequencing

Measuring total cell-free DNA (cfDNA) or cancer-specific mutations herein has presented as new tools in aiding the treatment of cancer patients. Studies show that total cfDNA bears prognostic value in metastatic colorectal cancer (mCRC) and that measuring cancer-specific mutations could supplement b...

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Publicado en:Transl Oncol
Main Authors: Demuth, Christina, Spindler, Karen-Lise Garm, Johansen, Julia S., Pallisgaard, Niels, Nielsen, Dorte, Hogdall, Estrid, Vittrup, Benny, Sorensen, Boe Sandahl
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press 2018
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Original article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085225/
https://ncbi.nlm.nih.gov/pubmed/30086420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.07.013
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