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Circulating Free DNA as Biomarker and Source for Mutation Detection in Metastatic Colorectal Cancer

BACKGROUND: Circulating cell-free DNA (cfDNA) in plasma has shown potential as biomarker in various cancers and could become an importance source for tumour mutation detection. The objectives of our study were to establish a normal range of cfDNA in a cohort of healthy individuals and to compare thi...

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Vydáno v:PLoS One
Hlavní autoři: Spindler, Karen Lise Garm, Pallisgaard, Niels, Andersen, Rikke Fredslund, Brandslund, Ivan, Jakobsen, Anders
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395277/
https://ncbi.nlm.nih.gov/pubmed/25875772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108247
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