Bromodomain and extra-terminal domain inhibition modulates the expression of pathologically relevant microRNAs in diffuse large B-cell lymphoma

Aberrant changes in microRNA expression contribute to lymphomagenesis. Bromodomain and extra-terminal domain inhibitors such as OTX015 (MK-8628, birabresib) have demonstrated preclinical and clinical activity in hematologic tumors. MicroRNA profiling of diffuse large B-cell lymphoma cells treated wi...

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Publicado en:Haematologica
Autores principales: Mensah, Afua A., Cascione, Luciano, Gaudio, Eugenio, Tarantelli, Chiara, Bomben, Riccardo, Bernasconi, Elena, Zito, Domenico, Lampis, Andrea, Hahne, Jens C., Rinaldi, Andrea, Stathis, Anastasios, Zucca, Emanuele, Kwee, Ivo, Gattei, Valter, Valeri, Nicola, Riveiro, Maria E, Bertoni, Francesco
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269312/
https://ncbi.nlm.nih.gov/pubmed/30076183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.191684
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