Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734

Bromodomain and extra-terminal domain (BET) proteins, cyclic adenosine monophosphate response element-binding protein (CBP), and the E1A-binding protein of p300 (EP300) are important players in histone acetylation. Preclinical evidence supports the notion that small molecules targeting these protein...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Spriano, Filippo, Gaudio, Eugenio, Cascione, Luciano, Tarantelli, Chiara, Melle, Federica, Motta, Giovanna, Priebe, Valdemar, Rinaldi, Andrea, Golino, Gaetanina, Mensah, Afua Adjeiwaa, Aresu, Luca, Zucca, Emanuele, Pileri, Stefano, Witcher, Michael, Brown, Bill, Wahlestedt, Claes, Giles, Francis, Stathis, Anastasios, Bertoni, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479962/
https://ncbi.nlm.nih.gov/pubmed/32882003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001879
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