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Synthesis of Disaccharides Containing 6-Deoxy-α-L-talose as Potential Heparan Sulfate Mimetics

A 6-deoxy-α-L-talopyranoside acceptor was readily prepared from methyl α-L-rhamnopyranoside and glycosylated with thiogalactoside donors using NIS/TfOH as the promoter to give good yields of the desired α-linked disaccharide (69–90%). Glycosylation with a 2-azido-2-deoxy-D-glucosyl trichloroacetimid...

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Publicado en:Molecules
Main Authors: Fairweather, Jon K., Liu, Ligong, Karoli, Tomislav, Ferro, Vito
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268951/
https://ncbi.nlm.nih.gov/pubmed/22895025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17089790
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