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Parallel Synthesis of Peptide-Like Macrocycles Containing Imidazole-4,5-dicarboxylic Acid

We prepared a series of peptide-like 14-membered macrocycles containing an imidazole-4,5-dicarboxylic acid scaffold by using known coupling reagents and protecting group strategies. Yields of the purified macrocycles were poor on average, yet seemingly independent of amino acid substitution or stere...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Xu, Zhigang, Wheeler, Kraig A., Baures, Paul W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268944/
https://ncbi.nlm.nih.gov/pubmed/22569415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17055346
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