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Parallel Synthesis of an Imidazole-4,5-dicarboxamide Library Bearing Amino Acid Esters and Alkanamines

The imidazole-4,5-dicarboxylic acid scaffold is readily derivatized with amino acid esters and alkanamines to afford compounds with intramolecularly hydrogen bonded conformations that mimic substituted purines and therefore are hypothesized to be potential inhibitors of kinases through competitive b...

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Detalhes bibliográficos
Main Authors: Solinas, Rosanna, DiCesare, John C., Baures, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651155/
https://ncbi.nlm.nih.gov/pubmed/19078856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules13123149
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