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Parallel Synthesis of Peptide-Like Macrocycles Containing Imidazole-4,5-dicarboxylic Acid

We prepared a series of peptide-like 14-membered macrocycles containing an imidazole-4,5-dicarboxylic acid scaffold by using known coupling reagents and protecting group strategies. Yields of the purified macrocycles were poor on average, yet seemingly independent of amino acid substitution or stere...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Xu, Zhigang, Wheeler, Kraig A., Baures, Paul W.
Format: Artigo
Langue:Inglês
Publié: MDPI 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268944/
https://ncbi.nlm.nih.gov/pubmed/22569415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17055346
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