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Development of New Drugs for an Old Target — The Penicillin Binding Proteins

The widespread use of β-lactam antibiotics has led to the worldwide appearance of drug-resistant strains. Bacteria have developed resistance to β-lactams by two main mechanisms: the production of β-lactamases, sometimes accompanied by a decrease of outer membrane permeability, and the production of...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zervosen, Astrid, Sauvage, Eric, Frère, Jean-Marie, Charlier, Paulette, Luxen, André
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268044/
https://ncbi.nlm.nih.gov/pubmed/23095893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules171112478
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