A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates

Zika virus (ZIKV) causes severe neurologic complications and fetal aberrations. Vaccine development is hindered by potential safety concerns due to antibody cross-reactivity with dengue virus and the possibility of disease enhancement. In contrast, passive administration of anti-ZIKV antibodies engi...

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Publicado no:Cell Rep
Main Authors: Keeffe, Jennifer R., Van Rompay, Koen K.A., Olsen, Priscilla C., Wang, Qiao, Gazumyan, Anna, Azzopardi, Stephanie A., Schaefer-Babajew, Dennis, Lee, Yu E., Stuart, Jackson B., Singapuri, Anil, Watanabe, Jennifer, Usachenko, Jodie, Ardeshir, Amir, Saeed, Mohsan, Agudelo, Marianna, Eisenreich, Thomas, Bournazos, Stylianos, Oliveira, Thiago Y., Rice, Charles M., Coffey, Lark L., MacDonald, Margaret R., Bjorkman, Pamela J., Nussenzweig, Michel C., Robbiani, Davide F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268006/
https://ncbi.nlm.nih.gov/pubmed/30403995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.031
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