Oleandrin synergizes with cisplatin in human osteosarcoma cells by enhancing cell apoptosis through activation of the p38 MAPK signaling pathway

PURPOSE: Our previous studies have reported the antitumor effect of oleandrin on osteosarcoma; however, its chemosensitizing effect in osteosarcoma treatment is still unknown. Therefore, we explored the sensitizing effects of oleandrin to cisplatin in osteosarcoma and investigated the potential mech...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Yong, Lei, Ma, Yunlong, Zhu, Bin, Liu, Xiao, Wang, Peng, Liang, Chen, He, Guanping, Zhao, Zhigang, Liu, Zhongjun, Liu, Xiaoguang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267710/
https://ncbi.nlm.nih.gov/pubmed/30267330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-018-3692-7
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