Crosstalk between autophagy and apoptosis contributes to ZnO nanoparticles-induced human osteosarcoma cell death

Killing osteosarcoma cells by zinc oxide nanoparticles (ZnO NPs) and its underlying sub-cellular mechanism have never been studied. Here we find that the NPs induced crosstalk between apoptosis and autophagy, which lead to osteosarcoma cell death. Specifically, the NP uptake promotes autophagy by in...

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Udgivet i:Adv Healthc Mater
Main Authors: He, Guanping, Ma, Yunlong, Zhu, Ye, Yong, Lei, Liu, Xiao, Wang, Peng, Liang, Chen, Yang, Chenlong, Zhao, Zhigang, Hai, Bao, Pan, Xiaoyu, Liu, Zhongjun, Liu, Xiaoguang, Mao, Chuanbin
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310009/
https://ncbi.nlm.nih.gov/pubmed/29900694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201800332
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