A Physiologically-Based Pharmacokinetic Model to Describe Ciprofloxacin Pharmacokinetics Over the Entire Span of Life

BACKGROUND: Physiologically-based pharmacokinetic (PBPK) modeling has received growing interest as a useful tool for the assessment of drug pharmacokinetics by continuous knowledge integration. OBJECTIVE: The objective of this study was to build a ciprofloxacin PBPK model for intravenous and oral do...

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Dettagli Bibliografici
Pubblicato in:Clin Pharmacokinet
Autori principali: Schlender, Jan-Frederik, Teutonico, Donato, Coboeken, Katrin, Schnizler, Katrin, Eissing, Thomas, Willmann, Stefan, Jaehde, Ulrich, Stass, Heino
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2018
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Original Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267540/
https://ncbi.nlm.nih.gov/pubmed/29737457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0661-6
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