PKCε phosphorylation regulates the mitochondrial translocation of ATF2 in ischemia-induced neurodegeneration

BACKGROUND: Global cerebral ischemia triggers neurodegeneration in the hippocampal CA1 region, but the mechanism of neuronal death remains elusive. The epsilon isoform of protein kinase C (PKCε) has recently been identified as a master switch that controls the nucleocytoplasmic trafficking of ATF2 a...

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Publicado en:BMC Neurosci
Autores principales: Kumar, Varun, Weng, Yi-Chinn, Wu, Yu-Chieh, Huang, Yu-Ting, Chou, Wen-Hai
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267029/
https://ncbi.nlm.nih.gov/pubmed/30497386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-018-0479-z
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