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PKCε regulates ATF2 availability to alter mitochondrial permeability following genotoxic stress
The transcription factor ATF2 elicits oncogenic activities in melanoma and tumor suppressor activities in non-malignant skin cancer. Here we identify that ATF2 tumor suppressor function is determined by its ability to localize at the mitochondria, where it alters membrane permeability following geno...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615433/ https://ncbi.nlm.nih.gov/pubmed/22304920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.016 |
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