TET2 deficiency leads to stem cell factor–dependent clonal expansion of dysfunctional erythroid progenitors

Myelodysplastic syndromes (MDSs) are clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis. Anemia is the defining cytopenia of MDS patients, yet the molecular mechanisms for dyserythropoiesis in MDSs remain to be fully defined. Recent studies have revealed that heteroz...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Qu, Xiaoli, Zhang, Shijie, Wang, Shihui, Wang, Yaomei, Li, Wei, Huang, Yumin, Zhao, Huizhi, Wu, Xiuyun, An, Chao, Guo, Xinhua, Hale, John, Li, Jie, Hillyer, Christopher D., Mohandas, Narla, Liu, Jing, Yazdanbakhsh, Karina, Vinchi, Francesca, Chen, Lixiang, Kang, Qiaozhen, An, Xiuli
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2018
Konular:
Red Cells, Iron, and Erythropoiesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265651/
https://ncbi.nlm.nih.gov/pubmed/30254129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-05-853291
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