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Distinct roles for TET family proteins in regulating human erythropoiesis

The ten-eleven translocation (TET) family of proteins plays important roles in a wide range of biological processes by oxidizing 5-methylcytosine (5mC) to 5-hydroxy-methylcytosine. However, their function in erythropoiesis has remained unclear. We show here that TET2 and TET3 but not TET1 are expres...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Yan, Hongxia, Wang, Yaomei, Qu, Xiaoli, Li, Jie, Hale, John, Huang, Yumin, An, Chao, Papoin, Julien, Guo, Xinhua, Chen, Lixiang, Kang, Qiaozhen, Li, Wei, Schulz, Vincent P., Gallagher, Patrick G., Hillyer, Christopher D., Mohandas, Narla, An, Xiuli
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383871/
https://ncbi.nlm.nih.gov/pubmed/28167661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-736587
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