Extracellular vesicles in DLBCL provide abundant clues to aberrant transcriptional programming and genomic alterations

The biological role of extracellular vesicles (EVs) in diffuse large B-cell lymphoma (DLBCL) initiation and progression remains largely unknown. We characterized EVs secreted by 5 DLBCL cell lines, a primary DLBCL tumor, and a normal control B-cell sample, optimized their purification, and analyzed...

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Pubblicato in:Blood
Autori principali: Rutherford, Sarah C., Fachel, Angela A., Li, Sheng, Sawh, Seema, Muley, Ashlesha, Ishii, Jennifer, Saxena, Ashish, Dominguez, Pilar M., Caldas Lopes, Eloisi, Agirre, Xabier, Chambwe, Nyasha, Correa, Fabian, Jiang, Yanwen, Richards, Kristy L., Betel, Doron, Shaknovich, Rita
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2018
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265635/
https://ncbi.nlm.nih.gov/pubmed/29967128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-12-821843
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