DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers

DYRK1A, dual-specificity tyrosine phosphorylation-regulated kinase 1A, which is linked to mental retardation and microcephaly, is a member of the CMGC group of kinases. It has both cytoplasmic and nuclear functions, however, molecular mechanisms of how DYRK1A regulates gene expression is not well un...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Li, Shanshan, Xu, Chu, Fu, Yinkun, Lei, Pin-Ji, Yao, Yanhua, Yang, Wanli, Zhang, Ying, Washburn, Michael P, Florens, Laurence, Jaiswal, Manish, Wu, Min, Mohan, Man
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265467/
https://ncbi.nlm.nih.gov/pubmed/30137413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky754
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