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The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP

The homologous cellular coactivators p300 and CBP contain intrinsic lysine acetyl transferase (termed HAT) activity. This activity is responsible for acetylation of several sites on the histones as well as modification of transcription factors. In a previous study, we found that HBZ, encoded by the...

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Detalhes bibliográficos
Main Authors: Wurm, Torsten, Wright, Diana G., Polakowski, Nicholas, Mesnard, Jean-Michel, Lemasson, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401433/
https://ncbi.nlm.nih.gov/pubmed/22434882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks244
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