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The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP

The homologous cellular coactivators p300 and CBP contain intrinsic lysine acetyl transferase (termed HAT) activity. This activity is responsible for acetylation of several sites on the histones as well as modification of transcription factors. In a previous study, we found that HBZ, encoded by the...

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Hlavní autoři: Wurm, Torsten, Wright, Diana G., Polakowski, Nicholas, Mesnard, Jean-Michel, Lemasson, Isabelle
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401433/
https://ncbi.nlm.nih.gov/pubmed/22434882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks244
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