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Effects of β-subunit on gating of a potassium ion channel: Molecular simulations of cardiac IKs activation

Dynamic conformational changes of ion channel proteins during activation gating determine their function as carriers of current. The relationship between these molecular movements and channel function over the physiological timescale of the action potential (AP) has not been fully established due to...

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Detalles Bibliográficos
Publicado en:J Mol Cell Cardiol
Main Authors: Xu, Jiajing, Rudy, Yoram
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265052/
https://ncbi.nlm.nih.gov/pubmed/30292722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.10.003
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