Tracking evolution of aromatase inhibitor resistance with circulating tumour DNA analysis in metastatic breast cancer

BACKGROUND: Selection of resistance mutations may play a major role in the development of endocrine resistance. ESR1 mutations are rare in primary breast cancer but have high prevalence in patients treated with aromatase inhibitors (AI) for advanced breast cancer. We investigated the evolution of ge...

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Publicat a:Ann Oncol
Autors principals: Fribbens, Charlotte, Garcia Murillas, Isaac, Beaney, Matthew, Hrebien, Sarah, O’Leary, Ben, Kilburn, Lucy, Howarth, Karen, Epstein, Michael, Green, Emma, Rosenfeld, Nitzan, Ring, Alistair, Johnston, Stephen, Turner, Nicholas
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264798/
https://ncbi.nlm.nih.gov/pubmed/29045530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdx483
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