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Tracking evolution of aromatase inhibitor resistance with circulating tumour DNA analysis in metastatic breast cancer

BACKGROUND: Selection of resistance mutations may play a major role in the development of endocrine resistance. ESR1 mutations are rare in primary breast cancer but have high prevalence in patients treated with aromatase inhibitors (AI) for advanced breast cancer. We investigated the evolution of ge...

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Библиографические подробности
Опубликовано в: :Ann Oncol
Главные авторы: Fribbens, Charlotte, Garcia Murillas, Isaac, Beaney, Matthew, Hrebien, Sarah, O’Leary, Ben, Kilburn, Lucy, Howarth, Karen, Epstein, Michael, Green, Emma, Rosenfeld, Nitzan, Ring, Alistair, Johnston, Stephen, Turner, Nicholas
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264798/
https://ncbi.nlm.nih.gov/pubmed/29045530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdx483
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