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Inhibitory Activity of Flavonoids against Class I Phosphatidylinositol 3-Kinase Isoforms
Class I PI3 Kinase (PI3K) phosphorylates phosphatidylinositol 4,5-bisphophate (PIP2) to generate the second messenger phosphatidylinositol 3,4,5-trisphosphate (PIP3) and therefore plays an important role in fundamental cellular responses such as proliferation. There are four isoforms of class I PI3K...
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| 出版年: | Molecules |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6264676/ https://ncbi.nlm.nih.gov/pubmed/21694679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16065159 |
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